Alanine aminotransferase (ALT), an enzyme predominantly found in hepatocytes, is a critical biomarker for assessing liver health. Sudden spikes in ALT levels—defined as a rapid increase exceeding three times the upper limit of normal (ULN)—often signal acute hepatocellular injury. This article explores the multifactorial etiology of abrupt ALT elevations, emphasizing common and rare causes, diagnostic […]